Btg2 proliferation
WebThus, the mutation of BTG2 may result in the dysfunction of tumor-repressor role of BTG2, and thereby contribute to malignant proliferation of B-cells in PT-DLBCL. In addition, we observed that 24% of patients were mutated in PRDM1 and were associated with shorter OS ( P =0.040, Table 3 ). WebMar 6, 2012 · The objective of the study was to investigate the impact of the B cell translocation gene 2 (BTG2) on lung cancer cell growth, proliferation, metastasis, and …
Btg2 proliferation
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WebOct 13, 2024 · B-cell translocation gene 2 (BTG2) is a crucial regulator in GLP-1-induced insulin gene expression and insulin secretion via upregulation of pancreatic duodenal homeobox-1 (PDX-1) in pancreatic beta-cells. These findings demonstrate the gonadotropin stimulation of Btg2 in the ovary and, the physical interaction of Btg2 with Ant2 in … WebA functional and biochemical interaction of TIS21(/BTG2/PC3) with Forkhead box M1 (FoxM1), essential transcription factor for hepatocyte regeneration and a master regulator of mitotic gene expression, was explored. ... Forced expression of TIS21 impaired growth, proliferation, and tumorigenic potential of Huh7 cells. At the mechanistic level ...
Protein BTG2 also known as BTG family member 2 or NGF-inducible anti-proliferative protein PC3 or NGF-inducible protein TIS21, is a protein that in humans is encoded by the BTG2 gene (B-cell translocation gene 2) and in other mammals by the homologous Btg2 gene. This protein controls cell cycle … See more A number of studies in vivo have shown that BTG2 expression is associated with the neurogenic asymmetric division in neural progenitor cells. Tis21-GFP has been used as a neurogenic marker because it is not expressed until … See more BTG2 has been shown to inhibit medulloblastoma, the very aggressive tumor of cerebellum, by inhibiting the proliferation and triggering the differentiation of the … See more • Puisieux A, Magaud JP (April 1999). "[Mechanisms of BTG2 activity, a transcriptional target of p53: evidences and hypothesis]". Bulletin du Cancer. 86 (4): 358–64. See more BTG2 has been shown to interact with PRMT1, HOXB9, CNOT8 and HDAC1 HDAC4 and HDAC9. It has also been studied with See more • Human BTG2 genome location and BTG2 gene details page in the UCSC Genome Browser. • Overview of all the structural information … See more WebApr 7, 2024 · BTG2 is expressed at low levels in multiple cancers and might therefore act as a tumor suppressor. 25 , 26 , 27 BTG2 plays an important role in cell proliferation, migration, invasion and drug resistance. 28 , 29 Little research has been performed on the biological behavior of BTG2 in response to IR stress.
WebMar 21, 2024 · BTG2 regulates hepatic glucose homeostasis via induction of orphan nuclear receptor Nur77 in diabetic mouse model. pro-apoptotic pathway of CRP-CD32-Nox2-p53 … WebMar 30, 2024 · Aberrations in FAS and PTEN co-occurred significantly (Q < 0.05), and a significant co-occurrence between PIM1, CD79B, and BTG2 (Q < 0.1) was found, especially in cases that relapsed early (Supplementary Figures S4-S5).
WebApr 18, 2024 · Recent studies have indicated that BTG2 is highly expressed in heart and skeletal muscle and that the expression levels increase during C2C12 myoblast differentiation . Moreover, BTG2 downregulation blocked C2C12 myoblast differentiation . However, the role of BTG2 in the proliferation and differentiation of myoblasts is not …
WebSep 14, 2024 · The overexpression of BTG2 in A549 cells causes cellular G1 phase arrest but did not affect cell proliferation, accompanied by increased activation of NF-κB. Our data indicate that BTG2 overexpression may trigger an autoregulatory prosurvival NF- κ B pathway, which is resistant to environmental intervention owing to an increased level of … reisterstown business centerWebApr 11, 2024 · E U2OS cells were treated as in (A) and their growth was assessed after 72 h culture using the cell proliferation reagent WST-1. Data are represented as mean ± SD of three independent experiments. reisterstown chocolate deliveryWebFeb 25, 2016 · BTG2 interacts with CAF1 deadenylase through its APRO domain, a defining feature of BTG/Tob factors. ... Importantly, we also show that the interaction of BTG2 with the first RRM domain of PABPC1 is required for BTG2 to control cell proliferation. Publication types Research Support, Non-U.S. Gov't MeSH terms Blotting, Western ... reisterstown car careWebMar 6, 2012 · The objective of the study was to investigate the impact of the B cell translocation gene 2 (BTG2) on lung cancer cell growth, proliferation, metastasis, and other biological characteristics and to provide experimental evidence for the biological treatment of human lung cancer. A pcDNA3.1-BTG2 eukaryotic expression vector was … produce portland venueWebThe closest homolog of BTG1 is BTG2, which also controls the proliferation and differentiation of adult neural stem cells; the role of BTG2, however, appears to differ from that of BTG1 being probably more relevant in controlling the terminal differentiation of neural stem and progenitor cells in the adult neurogenic niches. reisterstown breweryWebBTG2 stimulates mRNA deadenylation via CAF1 activation through interaction with PABPC1. Interaction of BTG2 with the first RRM domain of PABPC1 is required for … produce powder loader factoryWebThe B cell translocation gene 1 (BTG1) and BTG2 play a key role in a wide range of cellular activities including proliferation, apoptosis, and cell growth via modulating a variety of central biological steps such as transcription, post-transcriptional, and translation. BTG1 and BTG2 have been identi … reisterstown community times