WebDec 23, 2002 · The four-way DNA junction is structurally polymorphic (reviewed in ref. 6 ). In the absence of divalent metal ions, the center is open and the four helical arms are directed towards the... WebSep 13, 2024 · p53 plays critical roles in regulating cell cycle, apoptosis, senescence and metabolism and is commonly mutated in human cancer. These roles are achieved by interaction with other proteins, but particularly by interaction with DNA. As a transcription factor, p53 is well known to bind consensus target sequences in linear B-DNA. Recent …
Fabrication of Electrochemical Influenza Virus Junction and …
WebDec 1, 2015 · PNA–DNA four-way junctions are composed of helices that are intermediate between A- and B-DNA; the apparent level (s) of A-form structure correlate with PNA content. The single-PNA constructs favor B-DNA structures and possess enhanced T m values in high Mg +2. WebFeb 8, 2024 · In this paper, we have performed molecular dynamics simulation on the four-way DNA junction by taking the sequence consisting of Guanine (G) and Cytosine (C) base pairs only. At the outset, we would like to mention the speciality of this molecule, it consists of ten bases in each strand and first two bases along the 5′ end was left free as ... how to impress a guy over text
The Structure of DNA Four-Way Junctions SpringerLink
WebJun 6, 1995 · Competition binding experiments demonstrate that four-way junctions (4WJ) are more stable than three-way junctions (3WJ), when no unpaired bases are included at … Webof the B-DNA duplexes and the associated patterns of hydration in the major and minor grooves only minimally. This supports the idea that a DNA four-way junction can be … WebDec 20, 1987 · The electrophoretic mobilities of the extended junctions differ in a manner which indicates that the junction is not a completely flexible structure; nor is it … jolie mctavish obituary