Hollow mno2 as a tumor-microenvironment
Nettet27. feb. 2024 · An activatable theranostic platform based on multifunctional MnO 2 -coated mesoporous silica nanoparticles (MS@MnO 2 NPs) has been developed for MRI-monitored combination chemotherapy and chemodynamic therapy (CDT). ADS=antioxidant defense system. Abstract NettetHerein, an intelligent biodegradable hollow manganese dioxide (H-MnO 2 ) nano-platform is developed for not only tumor microenvironment (TME)-specific imaging and on-demand drug release, but also modulation of hypoxic TME to enhance cancer therapy, resulting in comprehensive effects favoring anti-tumor immune responses. With hollow …
Hollow mno2 as a tumor-microenvironment
Did you know?
NettetOnce exposed to a tumor microenvironment, ... Cui Y, Yan X, et al. Controlled preparation of MnO2 hierarchical hollow nanostructures and their application in water treatment. Adv ... Zhao Z, Fan H, Zhou G, et al. Activatable fluorescence/MRI bimodal platform for tumor cell imaging via MnO2 nanosheet-aptamer nanoprobe. J Am Chem … Nettet根據世界衛生組織的數據，到2024年癌症相關死亡人數將增加到約1.5億。在90％的人類癌症相關死亡中，惡性轉移是主要原因。目前臨床上的主流療法，例如手術切除術，化學療法和放射療法，對於已經擴散和轉移的晚期癌症功效很有限，且對正常組織與細胞會造成附帶傷害，嚴重影響患者生活品質。
Nettet14. apr. 2024 · Tumor microenvironment is a heterogeneous and dynamic entity having complex interaction of tumor cells with their adjacent microenvironment that comprises various acellular components of extracellular matrix (ECM) altering their physical and chemical properties as well as communication with nearby cellular components such as … Nettet1. mai 2024 · 1. Introduction. The tumor microenvironment is an important triggering factor for intelligent responsive nanocarrier in the field of drug controlled release [[1], [2], [3]].As we all know, tumor microenvironment is usually characterized by a high concentration of glutathione (GSH) [4], H 2 O 2 [5], acidity [6], and hypoxia [7], which …
NettetThe morphology control of the MnO 2 hollow spheres can be easily achieved by altering the mass ratio of Pluronic F-127 to silica spheres. Material characterizations reveal that urchin-like hollow spheres possess the highest BET surface area of 233.4 m 2 g −1 among the diverse morphologies. Nettet10. apr. 2024 · Results shows that MP@H-MnO2-Dox-Col can increase the Dox effect with low cardiotoxicity based on multi-functions of effective penetration in tumor tissue, alleviating hypoxia in TME, pH sensitive drug release as well as targeted delivery of Dox. Doxorubicin (Dox) has been recommended in clinical guidelines for the standard-of …
Nettet5. apr. 2024 · 刘美玲，理学博士，教授，博士生导师，湖南省芙蓉学者青年学者，湖南省青年骨干教师培养对象。. 2006年硕士毕业留校工作，2012年获得理学博士学位。. 2024年6月-2024年6月在加州大学洛杉矶分校访学。. 主要从事光、电分析化学与传感和纳米材料的表 …
Nettet15. feb. 2024 · In this study, platelet membrane (PLTM) biomimetic hollow MnO 2 nanoparticles were prepared and these were investigated for delivery of bufalin. Additionally, these nanoparticles, in response to the tumor microenvironment, showed rapid drug release and generated the hydroxyl radicals (HO) by the Fenton reaction … paw patrol underwater rescue toysNettet26. mai 2024 · The tumor microenvironment (TME) is characterized by oxygen-deficient solid tumors. Hypoxic conditions significantly promote tumor heterogeneity and increase metastatic spread [1,2,3].Furthermore, undesirable angiogenesis and immunosuppression are caused by disordered metabolism and unstable genome phenotype accelerated in … paw patrol underwear for toddler boysNettetMnCO can react with the H 2 O 2 to generate CO, powerfully damaging the tumor. Both in vitro and in vivo experiments indicate that the ZCM system is both safe and has … paw patrol ultimate toysNettet12. okt. 2024 · Abstract. Herein, an intelligent biodegradable hollow manganese dioxide (H-MnO 2) nano-platform is developed for not only tumor microenvironment (TME) … paw patrol unterhosen mädchenNettet13. mai 2024 · Abstract. Hollow mesoporous copper sulfide nanoparticles (HMCuS NPs) are advantageous for loading small-molecule therapeutic drugs coupled with … paw patrol underwear girlsNettetResearchGate paw patrol used toysNettetIn this case, MnO 2 nanosheets serve as (i) a nanocarrier and fluorescence quencher for the photosensitizer Ce6, (ii) a degradable material that is activated by the tumor … screenshot one word or two words