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Myh11-cre

WebInducible VSMC Pparγ KO mice are generated by crossing mice expressing a fusion protein of Cre recombinase with the modified estrogen receptor ligand binding domain (CreER T2) under the control of the smooth muscle myosin heavy chain (smmhc, myh11) with mice having loxP sites flanking exon 2 of the Pparγ gene (Pparγ Flox/Flox). WebThe Myh11-CreERT2mouse line (Cre+) has gained increasing application because of its high lineage specificity relative to other Cre drivers targeting smooth muscle cells (SMCs). This Cre allele, however, was initially inserted into the Y chromosome (X/YCre+), which excluded its application in female mice.

Myh11-Cre is not limited to peritubular myoid cells and interaction ...

Web18 aug. 2024 · 血管平滑肌及血管内皮组织特异性cre工具鼠.PDF,血管平滑肌及血管内皮组织特异性cre 工具鼠 一、血管平滑肌特异性的cre 工具鼠： 1. Tagln-cre Tagln （Transgelin ），又称为SM22 或SM22a，主要表达于平滑肌细胞中，属于微丝 连接蛋白家族。是目前血管平滑肌细胞条件性敲除最常用的cre 工具鼠启动子。 Web4 feb. 2024 · Whereas Myh11-CreERT2 -mediated knockout of Srf resulted in a lethal intestinal phenotype, loss of Srf with Itga8-CreERT2 ( SrfItga8) revealed viable mice with attenuated vascular SMC contractile gene expression, but no … sneakers with lights for adults https://ramsyscom.com

019079 - SMMHC-iCreER[T2] Strain Details - The Jackson …

Web21 apr. 2024 · 7.Chen SR*, Liu YX*. (2016) Myh11-Cre is not limited to peritubular myoid cells and interaction between Sertoli and peritubular myoid cells needs investigation. Proc Natl Acad Sci U S A, 113(17):E2352. 8.Chen SR*, Chen M, Deng SL, Hao XX, Wang XX, Liu YX*. (2016) Sodium-hydrogen exchanger NHA1 and NHA2 control sperm motility and … Web2 dec. 2024 · Purpose: To establish Myh11 as a marker of a subset of corneal endothelial cells (CECs), and to demonstrate the feasibility of restoring the corneal endothelium with … WebB, Myh11-Cre/ERT2-mTmG mice were injected with TMX or oil control for 5 consecutive days. Confocal microscopy for mT and mG fluorescence was performed in the indicated … sneakers with good arch support for flat feet

Novel Myh11 Dual Reporter Mouse Model Provides Definitive …

Category:A New Autosomal Myh11-CreERT2 Smooth Muscle Cell Lineage …

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Myh11-cre

Myh11+ microvascular mural cells and derived …

http://www.informatics.jax.org/allele/MGI:2653286 Web22 jul. 2016 · We used Rosa26 nLacZ reporter mice carrying either Tcf21 MCM (resident fibroblasts) 7, LysM Cre (macrophages) 35, Cdh5 Cre (endothelial cells) 36 and Myh11 CreERT2 (smooth muscle cells) 37 along ...

Myh11-cre

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Web036935 B6.FVB(Cg)-Tp(X)1Soff Tg(Myh11-icre/ERT2)1Soff /ZjngJ SMMHC-CreER T2 transgenic mice allow sufficient Myh11 -driven tamoxifen-inducible Cre expression in … http://www.informatics.jax.org/allele/MGI:3819270

WebObjective: Myh11 encodes a myosin heavy chain protein that is specifically expressed in smooth muscle cells (SMCs) and is important for maintaining vascular wall stability. The … Web2 dec. 2024 · Methods: Intraperitoneal administration of tamoxifen and (Z)-4-hydroxytamoxifen eyedrops were used to trace the lineage of Myh11-expressing cells with the Myh11-Cre-ERT2-flox-tdTomato mouse model. Immunostaining and Western blot characterized marker expression and spatial distribution of Myh11-Lin(+) cells in the …

http://www.labcell.cn/mod_product-view-p_id-4629.html WebNational Center for Biotechnology Information

WebMutation details: The transgene consists of a mouse Myh11 promoter, a cre recombinase gene, an internal ribosome entry site (IRES) and an enhanced GFP gene. 16 kb of …

Web19 apr. 2024 · High expression of molecules mediating cell contractility (Tagln, Actg2, and Myh11) ... Since the Ccl19-Cre transgene highlight FRCs in all SLOs 32,34,35, ... roadtrek playWeb25 sep. 2024 · Cultured Myh11+ mural cells do continue to express Myh11 once injected intravitreally, but at significantly reduced level compared to Myh11 expression on … roadtrek optional front seat bedWebMutation details : The transgene consists of a mouse Myh11 promoter, a cre recombinase gene, an internal ribosome entry site (IRES) and an enhanced GFP gene. 16 kb of mouse Myh11 promoter sequences was used to drive the bicistronic transgene expression in smooth muscle cells. The promoter has also been reported to be active in female germ … roadtrek play rvWeb037658 - Myh11-CreER [T2]-RAD Strain Details. Technical Information Scientists. Overview. How it's Used. sneakers with individual toesWebMutation details : The mouse promoter from BAC clone 26630 was used to drive inducible icre expression in smooth muscle cells. An frt-flanked beta-lactamase gene contained within the cre/ESR1 cassette was removed by flp mediated recombination prior to micro-injection into fertilized oocytes. No line information was given. roadtrek rv for sale by ownerWebCre 蛋白是一种重组酶，是causes recombination的缩写，于1981 年从 P1 噬菌体中被发现，属于 λInt 酶超基因家族。Cre 重组酶基因编码区序列全长1029bp，编码 38kDa 蛋白 … sneakers with large starWeb9 nov. 2024 · cre 平滑肌 血管 tagln 异性 工具. 血管平滑肌及血管内皮组织特异性cre工具鼠一、血管平滑肌特异性的cre工具鼠：Tagln-creTagln（Transgelin），又称为SM22或SM22a，主要表达于平滑肌细胞中，属于微丝连接蛋白家族。. 是目前血管平滑肌细胞条件性敲除最常用的cre工具鼠 ... sneakers with lehenga