Phospholipase a2 receptor antibody panel
WebThe Phosphlipase A2 receptor (PLA2R) was recently discovered as a target autoantigen in patients with idiopathic membranous nephropathy (IMN). Autoantibodies directed to … WebAnti-PLA2R antibody podocyte apoptosis protein binding actin Introduction The pathogenesis of membranous nephropathy (MN) involves in situ formation of subepithelial immune deposits that induce glomerular injury by damaging podocytes through complement-dependent processes [ 1 ].
Phospholipase a2 receptor antibody panel
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WebMar 8, 2024 · Phospholipases (PLs) are fundamental lipolytic enzymes for living organisms. They are classified in different families (A1, A2, B, C and D), distinguishable by the position where they induce lipid hydrolysis [1,2].The PLA2 family is involved in the cleavage of an sn-2 ester bond of the glycerophospholipid substrate, with the consequent generation of 1-acyl … WebApr 29, 2013 · An Anti-Phospholipase A 2 Receptor Quantitative Immunoassay and Epitope Analysis in Membranous Nephropathy Reveals Different Antigenic Domains of the Receptor Astrid Behnert, Marvin J. Fritzler, Beina Teng, Meifeng Zhang, Frank Bollig, Hermann Haller, Andrej Skoberne, Michael Mahler, Mario Schiffer
WebThe presence of antibodies against phospholipase A2 receptor (PLA2R-Abs) in serum at diagnosis is reported to be related to the rate of spontaneous remission in patients with idiopathic membranous nephropathy (IMN); however, there is still lack of enough samples to illustrate this problem.
WebThe M-type phospholipase A2 receptor (PLA2R) is a target autoantigen in adult idiopathic membranous nephropathy (MN), but the prevalence of autoantibodies against PLA2R is … WebBackground: The recent finding that phospholipase-A (2)-receptor antibodies (PLA (2)R-AB) may play a role in the development of primary membranous glomerulonephritis (MGN) …
WebApr 22, 2024 · The accuracy of the anti-phospholipase A2 receptor antibody in the diagnosis of idiopathic membranous nephropathy: A comparison of different cutoff values as measured by the ELISA method. Int. Urol.
WebAug 1, 2002 · The phospholipase A 2 receptor (PLA 2 R) is a type I transmembrane glycoprotein related to the C-type animal lectin family that includes the mannose receptor.PLA 2 R regulates a variety of biological responses elicited by specific types of secretory PLA 2 s (sPLA 2 s). Group IB sPLA 2 (sPLA 2-IB) acts as an endogenous PLA 2 … meaning of reference booksWebLp-PLA2病理學抗體： Lp-PLA2，也稱為脂蛋白相關磷脂酶 A2 (Lipoprotein-associated Phospholipase A2)或血小板活化因子乙酰水解酶 (platelet-activating factor acetylhydrolase , PAF-AH)，是一種由炎症細胞(inflammatory cells )產生的酶，其功能是使血小板活化因子(platelet-activating factor)失活和降 ... pediatric asthma exacerbation wikemWebMar 20, 2024 · The natural anti-PLA2R antibodies recognized the conformational structure of PLA2R which locates on the cell membrane of podocytes. The amount of natural IgG … meaning of referWebThe characterization of the phospholipase A2 receptor (PLA2R) as the major target antigen in primary MN and the detection of circulating autoantibodies in these patients is a major advance in understanding this disease. meaning of referee in jobWebSep 9, 2024 · Background Membranous nephropathy (MN) is an autoimmune disease induced by circulating antibodies against the podocyte protein phospholipase A2 receptor 1 (PLA2R1-ab) in 80% of patients and represents the leading cause of nephrotic syndrome in adults. PLA2R1-ab levels correlate with disease activity and treatment response. However, … pediatric asthma exacerbation guidelines 2018http://biopioneer.com.tw/?p=41025 pediatric asthma hpiWebIba1/AIF1抗體Vimentin antibody產品介紹: This gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. meaning of refereeing